STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PIK3CAPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta. (1068 aa)    
Predicted Functional Partners:
PIK3R1
Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1.
   
 0.999
PIK3R2
Phosphoinositide-3-kinase regulatory subunit alpha/beta/delta.
   
 0.997
PIK3R3
Phosphoinositide-3-kinase regulatory subunit alpha/beta/delta.
   
 0.996
RRAS
LOW QUALITY PROTEIN: ras-related protein R-Ras.
   
 0.995
MRAS
Ras-related protein M-Ras.
   
 0.994
PIK3R5
Phosphoinositide 3-kinase regulatory subunit 5 isoform X1.
   
 0.991
EGFR
Epidermal growth factor receptor isoform X1.
    
 0.989
RRAS2
Ras-related protein R-Ras2 isoform X1.
   
 0.982
PIK3CB
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1.
     
0.978
PIK3CD
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta.
     
0.978
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.