STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMAD6Mothers against decapentaplegic homolog 6. (500 aa)    
Predicted Functional Partners:
SMURF1
E3 ubiquitin-protein ligase SMURF1 isoform X1.
    
 0.994
SMURF2
E3 ubiquitin-protein ligase SMURF2 isoform X1.
    
 0.992
SMAD1
Mothers against decapentaplegic homolog 1.
   
0.984
SMAD9
Mothers against decapentaplegic homolog 9.
   
0.965
SMAD5
Mothers against decapentaplegic homolog 5.
   
0.961
SMAD7
Mothers against decapentaplegic homolog 7.
  
 
0.945
SMAD3
Mothers against decapentaplegic homolog 3.
   
0.944
SMAD2
Mothers against decapentaplegic homolog 2 isoform X1.
   
0.944
TGFBR1
TGF-beta receptor type-1.
   
 0.844
SMAD4
Mothers against decapentaplegic homolog 4.
    
0.792
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.