Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACVR2AActivin receptor type-2A isoform X1. (521 aa)    
Predicted Functional Partners:
INHBA
Inhibin beta A chain.
   
 0.990
INHBB
Inhibin beta B chain.
   
 0.986
ACVR1B
Activin receptor type-1B isoform X1.
  
0.986
BMP4
Bone morphogenetic protein 4 isoform X1.
    
 0.982
BMP2
Bone morphogenetic protein 2.
    
 0.982
BMPR1A
Bone morphogenetic protein receptor type-1A.
  
0.979
BMP6
Bone morphogenetic protein 6.
    
 0.972
ACVR1
Activin receptor type-1.
  
0.971
SMAD3
Mothers against decapentaplegic homolog 3.
   
 0.970
SMAD2
Mothers against decapentaplegic homolog 2 isoform X1.
   
 0.970
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
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