Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RCHY1RING finger and CHY zinc finger domain-containing protein 1 isoform X1. (261 aa)    
Predicted Functional Partners:
TP53
Cellular tumor antigen p53.
    
 0.994
POLH
DNA polymerase eta.
    
 0.979
AR
LOW QUALITY PROTEIN: androgen receptor.
    
 
 0.885
RPS27A
Ubiquitin-small subunit ribosomal protein S27Ae.
    
 0.820
ENSPCIP00000040403
annotation not available
    
 0.820
ENSPCIP00000045070
annotation not available
    
 0.820
MDM2
LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase Mdm2.
    
 
 0.807
POLI
DNA polymerase iota isoform X1.
    
 0.741
UBE2D1
Ubiquitin-conjugating enzyme E2 D1.
   
 0.720
ENSPCIP00000043722
annotation not available
    
 
 0.695
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
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