Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
POFUT1GDP-fucose protein O-fucosyltransferase 1 isoform X1. (385 aa)    
Predicted Functional Partners:
POFUT2
GDP-fucose protein O-fucosyltransferase 2.
   
 
 0.962
NOTCH1
LOW QUALITY PROTEIN: neurogenic locus notch homolog protein 1.
    
 0.850
ENSPCIP00000007226
Craniofacial development protein 2-like.
   
 
 0.848
NOTCH3
Neurogenic locus notch homolog protein 3 isoform X1.
    
 0.847
NOTCH4
Neurogenic locus notch homolog protein 4.
    
 0.819
F7
Coagulation factor VII.
    
   0.791
NOTCH2
LOW QUALITY PROTEIN: neurogenic locus notch homolog protein 2.
    
 0.739
SLC35D1
UDP-glucuronic acid/UDP-N-acetylgalactosamine transporter.
      
 0.624
PCSK2
Proprotein convertase subtilisin/kexin type 2.
   
  
 0.598
TSR3
Ribosome biogenesis protein TSR3 homolog isoform X1.
      
 0.588
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
Server load: low (14%) [HD]