Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CCM2LCerebral cavernous malformations 2 protein-like isoform X1. (597 aa)    
Predicted Functional Partners:
KRIT1
Krev interaction trapped protein 1 isoform X1.
    
 
 0.855
ITGB1BP1
Integrin beta-1-binding protein 1 isoform X1.
    
 
 0.814
RASIP1
LOW QUALITY PROTEIN: ras-interacting protein 1.
   
 
 0.783
PDCD10
Programmed cell death protein 10.
    
 
 0.736
MAP3K3
Mitogen-activated protein kinase kinase kinase 3 isoform X1.
    
 0.720
ENSPCIP00000038921
Uncharacterized protein KIAA0825 homolog isoform X1.
    
 
 0.585
PIBF1
Progesterone-induced-blocking factor 1 isoform X1.
    
 0.505
EFCAB2
EF-hand calcium-binding domain-containing protein 2 isoform X1.
    
 0.504
CHRAC1
Chromatin accessibility complex protein 1.
      
 0.502
TNPO2
Transportin-2 isoform X1.
    
 
 0.501
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.