Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-expression
Experiments
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[Homology]
Score
TPX2Targeting protein for Xklp2 isoform X1. (746 aa)    
Predicted Functional Partners:
AURKA
Aurora kinase A.
   
 0.998
KIF2C
Kinesin family member 2/24.
   
  
 0.985
AURKB
Aurora kinase B isoform X1.
   
 0.959
DLGAP5
Disks large-associated protein 5 isoform X1.
   
  
 0.949
CDK1
Cyclin-dependent kinase 1.
   
 0.945
BIRC5
Baculoviral IAP repeat-containing protein 5 isoform X1.
   
 0.930
PRC1
Protein regulator of cytokinesis 1 isoform X1.
   
 
 0.928
BUB1
Mitotic checkpoint serine/threonine-protein kinase BUB1.
   
  
 0.926
KIF11
Kinesin-like protein KIF11.
   
 
 0.925
HMMR
Hyaluronan mediated motility receptor.
   
 0.908
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
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