Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
IRF7Interferon regulatory factor 7 isoform X1. (512 aa)    
Predicted Functional Partners:
TBK1
Serine/threonine-protein kinase TBK1.
   
 0.978
TRAF6
TNF receptor-associated factor 6.
    
 0.974
IKBKE
Inhibitor of nuclear factor kappa-B kinase subunit epsilon isoform X1.
   
 0.973
CREBBP
LOW QUALITY PROTEIN: CREB-binding protein.
    
 0.972
EP300
E1A binding protein p300.
    
 0.969
IRF3
Interferon regulatory factor 3 isoform X1.
     
0.960
CHUK
Inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1.
    
 0.960
IRAK4
Interleukin-1 receptor-associated kinase 4 isoform X1.
    
 0.949
TICAM1
TIR domain-containing adapter molecule 1.
    
 0.948
IRAK1
Interleukin-1 receptor-associated kinase 1 isoform X1.
    
 0.940
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
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