STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PRLProlactin. (228 aa)    
Predicted Functional Partners:
PRLR
LOW QUALITY PROTEIN: prolactin receptor.
    
 0.998
ENSPCIP00000011302
Growth hormone.
   
0.984
LEP
Leptin.
   
 
 0.958
EPO
Erythropoietin.
     
 0.913
GHR
Growth hormone receptor.
  
  
 0.912
THPO
Thrombopoietin isoform X1.
     
 0.908
CSF3
Granulocyte colony-stimulating factor.
     
 0.906
CNTF
Ciliary neurotrophic factor.
     
 0.904
JAK2
LOW QUALITY PROTEIN: tyrosine-protein kinase JAK2.
     
 0.897
CRLF1
Cytokine receptor-like factor 1 isoform X1.
    
 0.880
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.