Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ALAS25-aminolevulinate synthase, erythroid-specific, mitochondrial isoform X1. (588 aa)    
Predicted Functional Partners:
ALAD
Delta-aminolevulinic acid dehydratase.
    
 0.976
SARDH
Sarcosine dehydrogenase, mitochondrial isoform X1.
  
 
 0.926
GLDC
Glycine dehydrogenase (decarboxylating), mitochondrial.
  
 
 0.917
GATM
Glycine amidinotransferase, mitochondrial.
     
 0.916
DAO
D-amino-acid oxidase.
  
 
 0.914
SHMT1
LOW QUALITY PROTEIN: serine hydroxymethyltransferase, cytosolic.
  
 
 0.912
SHMT2
Serine hydroxymethyltransferase, mitochondrial.
  
 
 0.912
AGXT
Alanine-glyoxylate transaminase / serine-glyoxylate transaminase / serine-pyruvate transaminase.
    
 0.912
PIPOX
Sarcosine oxidase / L-pipecolate oxidase.
  
 
 0.911
AGXT2
Alanine-glyoxylate transaminase / (R)-3-amino-2-methylpropionate-pyruvate transaminase.
    
 0.910
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
Server load: low (18%) [HD]