Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SPASTSpastin isoform X1. (617 aa)    
Predicted Functional Partners:
C1orf112
Uncharacterized protein C1orf112 homolog isoform X1.
   
 0.865
IST1
Vacuolar protein sorting-associated protein IST1.
    
 0.828
ENSPCIP00000036804
annotation not available
    
 0.828
RAD51
DNA repair protein RAD51 homolog 1.
  
 0.732
UBXN7
UBX domain-containing protein 7.
   
 0.719
WRN
Werner syndrome ATP-dependent helicase.
   
 0.655
CHMP6
Charged multivesicular body protein 6.
    
 0.645
CHMP2A
Charged multivesicular body protein 2A.
    
 0.638
CHMP3
Charged multivesicular body protein 3.
   
 0.629
ENSPCIP00000007871
annotation not available
    
 0.627
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
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