Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
SIK1Serine/threonine-protein kinase SIK1 isoform X1. (786 aa)    
Predicted Functional Partners:
CRTC2
CREB regulated transcription coactivator 2.
   
 0.962
GINS4
DNA replication complex GINS protein SLD5 isoform X1.
    
   0.814
AGPAT1
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha isoform X1.
      
 0.724
CRTC3
CREB-regulated transcription coactivator 3.
   
 
 0.594
RD3L
Protein RD3-like.
      
 0.578
ENSPCIP00000018707
annotation not available
    
 0.538
YWHAE
14-3-3 protein epsilon isoform X1.
    
 0.538
ENSPCIP00000026438
Nuclear factor interleukin-3-regulated protein isoform X1.
      
 0.534
MIDN
Midnolin.
      
 0.504
SIK2
Serine/threonine-protein kinase SIK2.
   
 0.499
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
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