Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TLR4Toll-like receptor 4. (832 aa)    
Predicted Functional Partners:
LY96
Lymphocyte antigen 96 isoform X1.
   
 0.999
TIRAP
Toll-interleukin 1 receptor (TIR) domain-containing adaptor protein.
   
 0.997
MYD88
Myeloid differentiation primary response protein MyD88.
    
0.997
HMGB1
High mobility group protein B1.
    
 0.997
TICAM2
TIR domain-containing adapter molecule 2.
    
 0.988
TRAF6
TNF receptor-associated factor 6.
   
 0.985
IRAK4
Interleukin-1 receptor-associated kinase 4 isoform X1.
   
 0.985
TICAM1
TIR domain-containing adapter molecule 1.
    
 0.978
TLR2
Toll-like receptor 2 isoform X1.
   
0.976
TRAF3
TNF receptor-associated factor 3.
   
 0.975
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.