Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSPCIP00000011302Growth hormone. (211 aa)    
Predicted Functional Partners:
GHR
Growth hormone receptor.
    
 0.997
PRL
Prolactin.
   
0.994
GHRL
Appetite-regulating hormone isoform X1.
   
 
 0.964
PRLR
LOW QUALITY PROTEIN: prolactin receptor.
   
 0.956
JAK2
LOW QUALITY PROTEIN: tyrosine-protein kinase JAK2.
     
 0.945
LEP
Leptin.
     
 0.928
EPO
Erythropoietin.
   
 
 0.911
CSF3
Granulocyte colony-stimulating factor.
     
 0.907
THPO
Thrombopoietin isoform X1.
     
  0.900
JAK3
Tyrosine-protein kinase JAK3.
     
 0.865
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
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