STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHARPINSHANK associated RH domain interactor. (375 aa)    
Predicted Functional Partners:
RNF31
E3 ubiquitin-protein ligase RNF31.
    
 0.996
RBCK1
RanBP-type and C3HC4-type zinc finger-containing protein 1 isoform X1.
  
0.989
TNFRSF1A
Tumor necrosis factor receptor superfamily member 1A.
    
 0.970
OTULIN
Ubiquitin thioesterase otulin isoform X1.
    
 0.883
CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD isoform X1.
    
 0.705
SHANK1
SH3 and multiple ankyrin repeat domains protein 1 isoform X1.
    
 0.671
RIPK1
Receptor-interacting serine/threonine-protein kinase 1 isoform X1.
   
 0.671
TNFRSF25
Tumor necrosis factor receptor superfamily member 25 isoform X1.
    
 0.643
PLEKHG6
Pleckstrin homology domain-containing family G member 6.
    
 0.643
PLEKHG5
Pleckstrin homology domain-containing family G member 5 isoform X1.
    
 0.643
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
Server load: medium (54%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.