STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MAP3K15Mitogen-activated protein kinase kinase kinase 15 isoform X1. (1349 aa)    
Predicted Functional Partners:
STIM2
Stromal interaction molecule 2 isoform X1.
    
   0.692
RPTOR
Regulatory-associated protein of mTOR isoform X1.
    
 0.567
NSUN2
TRNA (cytosine(34)-C(5))-methyltransferase.
 
 
    0.521
PRKAB2
5'-AMP-activated protein kinase, regulatory beta subunit.
    
 0.491
PRKAB1
5'-AMP-activated protein kinase, regulatory beta subunit.
    
 0.491
PRKAG3
Protein kinase AMP-activated non-catalytic subunit gamma 3.
   
 0.470
PRKAG1
5'-AMP-activated protein kinase subunit gamma-1 isoform X1.
   
 0.470
PRKAG2
5'-AMP-activated protein kinase subunit gamma-2 isoform X1.
   
 0.470
WDR90
WD repeat-containing protein 90.
    
 0.465
STIM1
Stromal interaction molecule 1 isoform X1.
    
   0.430
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.