Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CLUClusterin. (458 aa)    
Predicted Functional Partners:
APOE
Apolipoprotein E.
   
 
 0.691
FOS
Proto-oncogene protein c-fos.
      
 0.637
GUCD1
Protein GUCD1 isoform X1.
      
 0.571
DCTN4
Dynactin subunit 4.
      
 0.571
LRP8
LOW QUALITY PROTEIN: low-density lipoprotein receptor-related protein 8.
    
 0.568
XRCC6
X-ray repair cross-complementing protein 6 isoform X1.
    
 
 0.538
APOA4
Apolipoprotein A-IV isoform X1.
   
 0.526
FOSL2
Fos-related antigen 2 isoform X1.
      
 0.469
PON1
Serum paraoxonase/arylesterase 1-like.
    
 0.466
PLA2G7
Platelet-activating factor acetylhydrolase.
     
 0.464
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.