Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EYA2EYA transcriptional coactivator and phosphatase 2. (516 aa)    
Predicted Functional Partners:
SIX2
Homeobox protein SIX2 isoform X1.
   
 0.873
SIX1
Homeobox protein SIX1.
   
 0.873
SIX4
Homeobox protein SIX4.
   
 0.790
SIX5
Homeobox protein SIX5.
   
 0.712
DACH1
Dachshund homolog 1 isoform X1.
    
 
 0.686
ENSPCIP00000028472
annotation not available
    
 
 0.638
EYA1
Eyes absent homolog 1 isoform X1.
     
  0.618
EYA4
LOW QUALITY PROTEIN: eyes absent homolog 4.
     
  0.618
MEGF11
Multiple epidermal growth factor-like domains protein 11 isoform X1.
      
 0.595
WSCD2
WSC domain-containing protein 2.
      
 0.591
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
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