Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TPCN1Two pore calcium channel protein 1 isoform X1. (818 aa)    
Predicted Functional Partners:
TPCN2
LOW QUALITY PROTEIN: two pore calcium channel protein 2.
    
0.920
CD38
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 isoform X1.
     
 0.902
UNC79
Unc-79 homolog, NALCN channel complex subunit.
   
 0.846
CACNB1
Voltage-dependent L-type calcium channel subunit beta-1 isoform X1.
   
 0.533
IFT122
Intraflagellar transport protein 122 homolog isoform X1.
   
 0.532
CACNB2
Voltage-dependent L-type calcium channel subunit beta-2 isoform X1.
   
 0.506
CACNB3
LOW QUALITY PROTEIN: voltage-dependent L-type calcium channel subunit beta-3.
   
 0.506
IQCD
IQ domain-containing protein D.
      
 0.487
CACNB4
Voltage-dependent L-type calcium channel subunit beta-4 isoform X1.
   
 0.487
SLC38A7
Solute carrier family 38 (sodium-coupled neutral amino acid transporter), member 7/8.
      
 0.478
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
Server load: low (18%) [HD]