Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SPOPLSpeckle-type POZ protein-like. (394 aa)    
Predicted Functional Partners:
CUL3
Cullin 3.
   
 0.994
GLI2
Zinc finger protein GLI2 isoform X1.
   
 0.987
GLI3
Transcriptional activator GLI3 isoform X1.
   
 0.987
GLI1
LOW QUALITY PROTEIN: zinc finger protein GLI1.
   
 0.971
SUFU
Suppressor of fused homolog isoform X1.
     
 0.942
SPOP
Speckle-type POZ protein.
  
  
 
0.900
RBX1
E3 ubiquitin-protein ligase RBX1.
    
 0.893
CUL1
Cullin 1.
   
 0.798
ENSPCIP00000038320
Inverted formin-2-like isoform X1.
    
 
 0.787
DAXX
Death domain-associated protein 6 isoform X1.
    
 
 0.778
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
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