Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SQLESqualene monooxygenase isoform X1. (596 aa)    
Predicted Functional Partners:
FDFT1
Farnesyl-diphosphate farnesyltransferase.
  
 
 0.997
LSS
Lanosterol synthase isoform X1.
  
 
 0.997
NSDHL
Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating isoform X1.
   
 
 0.977
CYP51A1
Lanosterol 14-alpha demethylase.
  
 0.977
IDI1
Isopentenyl-diphosphate Delta-isomerase 1 isoform X1.
   
  
 0.959
MSMO1
Methylsterol monooxygenase 1.
   
 
 0.955
CH25H
Cholesterol 25-hydroxylase.
   
 
 0.955
HMGCS1
Hydroxymethylglutaryl-CoA synthase, cytoplasmic.
   
  
 0.952
MARCHF6
E3 ubiquitin-protein ligase MARCH6 isoform X1.
    
 
 0.942
DHCR7
7-dehydrocholesterol reductase isoform X1.
   
 
 0.941
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
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