STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IGF1Insulin-like growth factor I isoform X1. (229 aa)    
Predicted Functional Partners:
INSR
Insulin receptor isoform X1.
    
 0.965
IGF1R
Insulin-like growth factor 1 receptor.
    
 0.965
IGFBP3
Insulin-like growth factor-binding protein 3.
   
 0.950
INS
Insulin.
     
0.938
TGFA
Protransforming growth factor alpha isoform X1.
     
 0.914
EGF
Pro-epidermal growth factor isoform X1.
     
 0.908
PDGFB
Platelet-derived growth factor subunit B isoform X1.
     
 0.906
ERBB2
LOW QUALITY PROTEIN: receptor tyrosine-protein kinase erbB-2.
     
 0.904
EGFR
Epidermal growth factor receptor isoform X1.
     
 0.904
DCN
Decorin.
   
 
  0.903
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.