Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
UBR5LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase UBR5. (2668 aa)    
Predicted Functional Partners:
BUB1
Mitotic checkpoint serine/threonine-protein kinase BUB1.
    
   0.911
TRIP12
E3 ubiquitin-protein ligase TRIP12 isoform X1.
   
  
 0.875
BUB1B
Mitotic checkpoint serine/threonine-protein kinase BUB1 beta isoform X1.
    
   0.845
PAIP2
Polyadenylate-binding protein-interacting protein 2 isoform X1.
    
 
 0.839
ZUP1
Zinc finger with UFM1-specific peptidase domain protein.
    
 
 0.838
TP53
Cellular tumor antigen p53.
    
 
 0.836
ENSPCIP00000031082
annotation not available
    
 
 0.829
BUB3
Mitotic checkpoint protein BUB3 isoform X1.
    
 
 0.829
CTNNB1
LOW QUALITY PROTEIN: catenin beta-1.
    
 
 0.821
MCRS1
Microspherule protein 1.
    
   0.817
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
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