STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADAM17Disintegrin and metalloproteinase domain-containing protein 17 isoform X1. (824 aa)    
Predicted Functional Partners:
NOTCH1
LOW QUALITY PROTEIN: neurogenic locus notch homolog protein 1.
    
 0.951
TIMP3
Metalloproteinase inhibitor 3.
    
 0.946
ADAM10
Disintegrin and metalloproteinase domain-containing protein 10 isoform X1.
     
0.938
NOTCH2
LOW QUALITY PROTEIN: neurogenic locus notch homolog protein 2.
    
 0.916
NOTCH3
Neurogenic locus notch homolog protein 3 isoform X1.
    
 0.915
NOTCH4
Neurogenic locus notch homolog protein 4.
    
 0.914
TIMP2
Metalloproteinase inhibitor 2.
    
 0.730
ENSPCIP00000047740
Tumor necrosis factor receptor superfamily member 16.
     
 0.696
NCSTN
Nicastrin isoform X1.
    
 
 0.688
ALDH3A2
Fatty aldehyde dehydrogenase isoform X1.
      
 0.658
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.