Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
GAS1Growth arrest-specific protein 1. (360 aa)    
Predicted Functional Partners:
PTCH1
Protein patched homolog 1 isoform X1.
     
 0.969
SHH
Sonic hedgehog protein.
    
 0.967
IHH
Indian hedgehog protein.
    
 0.967
DHH
Desert hedgehog protein.
    
 0.966
PTCH2
Patched 2.
     
 0.960
BOC
Brother of CDO isoform X1.
    
 0.954
CDON
Cell adhesion molecule-related/down-regulated by oncogenes.
    
 0.953
LRP2
Low-density lipoprotein receptor-related protein 2 isoform X1.
     
 0.909
SMO
Smoothened homolog.
     
 0.709
GAS2
Growth arrest-specific protein 2.
      
 0.697
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
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