Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CDONCell adhesion molecule-related/down-regulated by oncogenes. (1255 aa)    
Predicted Functional Partners:
DHH
Desert hedgehog protein.
    
 0.996
PTCH1
Protein patched homolog 1 isoform X1.
    
 0.994
BOC
Brother of CDO isoform X1.
   
0.993
SHH
Sonic hedgehog protein.
    
 0.984
IHH
Indian hedgehog protein.
    
 0.983
PTCH2
Patched 2.
    
 0.979
GAS1
Growth arrest-specific protein 1.
    
 0.953
LRP2
Low-density lipoprotein receptor-related protein 2 isoform X1.
     
 0.910
SMO
Smoothened homolog.
   
 0.898
CDH4
Cadherin 4, type 1, R-cadherin.
   
 0.725
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
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