STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SYKTyrosine-protein kinase SYK isoform X1. (638 aa)    
Predicted Functional Partners:
VAV1
Guanine nucleotide exchange factor VAV.
   
 0.998
FCER1G
High affinity immunoglobulin epsilon receptor subunit gamma.
   
 0.997
PLCG1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X1.
   
0.997
CD247
T-cell surface glycoprotein CD3 zeta chain.
   
 0.996
PLCG2
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2.
   
0.995
TYROBP
LOW QUALITY PROTEIN: TYRO protein tyrosine kinase-binding protein.
   
 0.995
VAV3
Guanine nucleotide exchange factor VAV3.
   
 0.992
LCP2
Lymphocyte cytosolic protein 2 isoform X1.
   
 0.991
VAV2
Guanine nucleotide exchange factor VAV2 isoform X1.
   
 0.990
LYN
Tyrosine-protein kinase Lyn isoform X1.
  
0.988
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.