STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ARHGEF7Rho guanine nucleotide exchange factor 7. (853 aa)    
Predicted Functional Partners:
ITSN2
Intersectin-2.
   
 
0.934
GIT2
G protein-coupled receptor kinase interactor 2.
    
 0.854
GIT1
G protein-coupled receptor kinase interactor 1.
    
 0.851
CDC42
Cell division control protein 42 homolog isoform X1.
   
 0.784
PAK2
Serine/threonine-protein kinase PAK 2 isoform X1.
    
 0.781
ENSPCIP00000027419
annotation not available
    
 0.781
PAK1
LOW QUALITY PROTEIN: serine/threonine-protein kinase PAK 1.
    
 0.757
ENSPCIP00000047597
annotation not available
    
 0.757
PAK3
Serine/threonine-protein kinase PAK 3.
    
 0.757
CBL
E3 ubiquitin-protein ligase CBL isoform X1.
    
 0.727
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.