Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
APCLOW QUALITY PROTEIN: adenomatous polyposis coli protein. (1864 aa)    
Predicted Functional Partners:
AXIN1
Axin-1 isoform X1.
   
 0.996
CTNNB1
LOW QUALITY PROTEIN: catenin beta-1.
   
 0.996
AXIN2
LOW QUALITY PROTEIN: axin-2.
   
 0.990
GSK3B
Glycogen synthase kinase-3 beta isoform X1.
    
 0.989
CSNK1A1
Casein kinase I isoform X1.
    
 0.988
DVL1
Dishevelled segment polarity protein 1.
    
 0.979
SPATA13
Spermatogenesis-associated protein 13 isoform X1.
   
 0.974
ARHGEF4
Rho guanine nucleotide exchange factor 4-like isoform X1.
   
 0.974
DVL2
LOW QUALITY PROTEIN: segment polarity protein dishevelled homolog DVL-2.
    
 0.961
DVL3
Segment polarity protein dishevelled homolog DVL-3 isoform X1.
    
 0.961
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
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