Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
RTN4LOW QUALITY PROTEIN: reticulon-4. (1209 aa)    
Predicted Functional Partners:
RTN3
Reticulon-3 isoform X1.
   
0.992
BACE1
Beta-site APP-cleaving enzyme 1 (memapsin 2).
    
 0.947
BACE2
Beta-site APP-cleaving enzyme 2 (memapsin 1).
    
 0.939
ATL3
Atlastin-3 isoform X1.
   
 
 0.912
RTN4R
Reticulon-4 receptor isoform X1.
    
 0.895
LINGO1
Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein.
   
 0.889
ARL6IP5
PRA1 family protein 3.
   
 
 0.880
RTN1
LOW QUALITY PROTEIN: reticulon-1.
 
 
 
 0.856
OMG
Oligodendrocyte myelin glycoprotein.
    
 0.854
RTN2
Reticulon 2.
    
 
 0.840
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
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