STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FEN1Flap endonuclease 1. (374 aa)    
Predicted Functional Partners:
PCNA
Proliferating cell nuclear antigen.
  
 0.999
WRN
Werner syndrome ATP-dependent helicase.
  
 0.999
POLD1
DNA polymerase delta catalytic subunit isoform X1.
   
 0.993
LIG1
DNA ligase 1.
  
 0.987
MRE11
LOW QUALITY PROTEIN: double-strand break repair protein MRE11.
   
 0.983
APEX1
DNA-(apurinic or apyrimidinic site) lyase.
  
 0.980
DNA2
LOW QUALITY PROTEIN: DNA replication ATP-dependent helicase/nuclease DNA2.
   
 0.976
POLD2
DNA polymerase delta subunit 2.
   
 0.972
BLM
Bloom syndrome protein.
  
 0.968
RFC3
Replication factor C subunit 3/5.
   
 0.950
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.