Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
CYP2R1Vitamin D 25-hydroxylase. (509 aa)    
Predicted Functional Partners:
CYP27B1
Calcidiol 1-monooxygenase (25-hydroxyvitamin D3 1alpha-hydroxylase).
  
0.977
CYP24A1
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial.
  
0.952
GC
GC vitamin D binding protein.
   
  
 0.725
CYP27C1
All-trans-retinol 3,4-desaturase.
  
 
0.721
CDH17
LOW QUALITY PROTEIN: cadherin-17.
   
  
 0.691
DHCR7
7-dehydrocholesterol reductase isoform X1.
   
 0.683
CLDN1
LOW QUALITY PROTEIN: claudin-1.
     
 0.631
CYP27A1
Cytochrome P450 family 27 subfamily A member 1.
  
 
0.617
ENSPCIP00000036417
Cytochrome P450 3A24-like.
  
0.603
ENSPCIP00000036405
Cytochrome P450 3A4-like isoform X1.
  
0.602
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
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