Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AMPHAmphiphysin. (749 aa)    
Predicted Functional Partners:
BIN1
Bridging integrator 1.
    
 
0.999
DNM2
Dynamin-2 isoform X1.
   
 0.966
SYNJ1
Synaptojanin-1 isoform X1.
   
 
 0.929
DNM1
Dynamin-1 isoform X1.
   
 
 0.905
SH3GL2
LOW QUALITY PROTEIN: endophilin-A1.
   
 
 0.874
AP2A1
AP-2 complex subunit alpha-1 isoform X1.
    
 
 0.872
BIN2
Bridging integrator 2 isoform X1.
    
 
 0.868
AP2B1
AP-2 complex subunit beta isoform X1.
    
 
 0.862
AP2S1
AP-2 complex subunit sigma-1.
    
 
 0.854
AP2A2
Adaptor related protein complex 2 subunit alpha 2.
    
 
 0.849
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
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