Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NLRC3NLR family CARD domain-containing protein 3. (1029 aa)    
Predicted Functional Partners:
RIPK2
Receptor-interacting serine/threonine-protein kinase 2.
   
 0.621
ENSPCIP00000039162
annotation not available
   
   0.517
ENSPCIP00000039165
Ribonuclease pancreatic-like.
   
   0.517
TAB1
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 isoform X1.
   
 0.515
AMFR
E3 ubiquitin-protein ligase AMFR isoform X1.
    
 
 0.504
TRAF6
TNF receptor-associated factor 6.
   
 0.501
ENSPCIP00000019460
Apoptosis-associated speck-like protein containing a CARD.
   
 0.497
ENSPCIP00000019467
Apoptosis-associated speck-like protein containing a CARD.
   
 0.497
NMRK1
Nicotinamide riboside kinase 1 isoform X1.
   
  
 0.497
ENSPCIP00000003034
Probable palmitoyltransferase ZDHHC11 isoform X1.
      
 0.492
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
Server load: low (12%) [HD]