Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MSH4MutS protein homolog 4 isoform X1. (956 aa)    
Predicted Functional Partners:
MSH5
MutS protein homolog 5 isoform X1.
  
0.994
MLH3
LOW QUALITY PROTEIN: DNA mismatch repair protein Mlh3.
 
 0.962
PMS1
LOW QUALITY PROTEIN: PMS1 protein homolog 1.
 
 0.934
MLH1
DNA mismatch repair protein Mlh1 isoform X1.
 
 0.921
RAD51
DNA repair protein RAD51 homolog 1.
   
 0.871
BLM
Bloom syndrome protein.
  
 0.824
TOP3A
DNA topoisomerase 3-alpha.
  
 0.815
PMS2
Mismatch repair endonuclease PMS2 isoform X1.
 
 0.805
DMRT1
Doublesex- and mab-3-related transcription factor 1.
    
 
 0.798
ENSPCIP00000046034
annotation not available
   
 
 0.795
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
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