Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PTPRBReceptor-type tyrosine-protein phosphatase beta isoform X1. (2214 aa)    
Predicted Functional Partners:
CTNNB1
LOW QUALITY PROTEIN: catenin beta-1.
    
 0.915
CDH5
Cadherin 5, type 2, VE-cadherin.
   
 0.856
ADGRF5
LOW QUALITY PROTEIN: adhesion G protein-coupled receptor F5.
   
 
 0.836
TEK
Endothelial-specific receptor tyrosine kinase.
   
 0.721
EGFR
Epidermal growth factor receptor isoform X1.
    
 0.599
INPP1
Inositol polyphosphate 1-phosphatase.
      
 0.513
TIE1
Tyrosine-protein kinase receptor Tie-1.
   
 0.511
SLC25A12
Solute carrier family 25 (mitochondrial aspartate/glutamate transporter), member 12/13.
      
 0.507
TP73
LOW QUALITY PROTEIN: tumor protein p73.
      
 0.492
CNTN1
Contactin 1.
    
 0.489
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
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