Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
RFWD3E3 ubiquitin-protein ligase RFWD3 isoform X1. (762 aa)    
Predicted Functional Partners:
RPA3
Replication protein A 14 kDa subunit.
    
 
 0.950
RPA1
Replication protein A 70 kDa DNA-binding subunit isoform X1.
   
 
 0.936
PRIMPOL
DNA-directed primase/polymerase protein isoform X1.
    
 
 0.916
SMARCAL1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1.
    
 
 0.863
WRN
Werner syndrome ATP-dependent helicase.
   
 
 0.841
WDR59
WD repeat-containing protein 59 isoform X1.
      
 0.804
GLG1
Golgi apparatus protein 1.
    
 
 0.771
FA2H
4-hydroxysphinganine ceramide fatty acyl 2-hydroxylase.
 
    
 0.722
TIMELESS
Protein timeless homolog.
   
 
 0.722
B2M
Beta-2-microglobulin.
    
 
 0.700
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
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