Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
IRF9Interferon regulatory factor 9. (413 aa)    
Predicted Functional Partners:
STAT1
Signal transducer and activator of transcription 1-alpha/beta.
   
 0.999
STAT2
Signal transducer and activator of transcription 2 isoform X1.
   
 0.999
TYK2
Non-receptor tyrosine-protein kinase TYK2.
    
 0.991
JAK1
Tyrosine-protein kinase JAK1 isoform X1.
    
 0.990
STAT4
Signal transducer and activator of transcription 4 isoform X1.
   
 0.989
ISG15
Ubiquitin cross-reactive protein.
   
 0.988
STAT3
Signal transducer and activator of transcription 3 isoform X1.
   
 0.981
STAT6
Signal transducer and activator of transcription 6 isoform X1.
   
 0.969
ENSPCIP00000053040
Signal transducer and activator of transcription 5B isoform X1.
   
 0.959
IFNAR2
LOW QUALITY PROTEIN: interferon alpha/beta receptor 2.
    
 0.916
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.