Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
HSD17B217beta-estradiol 17-dehydrogenase / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+). (383 aa)    
Predicted Functional Partners:
HSD17B1
17beta-estradiol 17-dehydrogenase.
  
 
0.989
DHRS11
17beta-estradiol 17-dehydrogenase / 3beta-hydroxysteroid 3-dehydrogenase.
  
 
 0.985
HSD17B8
Estradiol 17-beta-dehydrogenase 8 isoform X1.
  
 
 0.950
SRD5A1
3-oxo-5-alpha-steroid 4-dehydrogenase 1.
   
 
 0.949
HSD11B1
Corticosteroid 11-beta-dehydrogenase isozyme 1 isoform X1.
  
 
0.949
HSD17B12
17beta-estradiol 17-dehydrogenase / very-long-chain 3-oxoacyl-CoA reductase.
  
  
 0.948
CYP19A1
Aromatase isoform X1.
    
 0.946
ENSPCIP00000023837
Steroid 17alpha-monooxygenase / 17alpha-hydroxyprogesterone deacetylase.
   
 0.940
SRD5A3
3-oxo-5-alpha-steroid 4-dehydrogenase 3 / polyprenol reductase.
     
 0.939
HSD3B2
3beta-hydroxy-Delta5-steroid dehydrogenase / steroid Delta-isomerase.
   
 
 0.930
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
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