Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TRIM3Tripartite motif-containing protein 3 isoform X1. (776 aa)    
Predicted Functional Partners:
TRIM2
Tripartite motif-containing protein 2 isoform X1.
   
   0.845
ACTN1
Alpha-actinin-1 isoform X1.
   
 
 0.720
ACTN4
Alpha-actinin-4 isoform X1.
   
 
 0.720
HGS
LOW QUALITY PROTEIN: hepatocyte growth factor-regulated tyrosine kinase substrate.
    
 
 0.709
TRIM44
Tripartite motif-containing protein 44 isoform X1.
    
 
 0.652
LRRC8E
LOW QUALITY PROTEIN: volume-regulated anion channel subunit LRRC8E.
    
 0.614
UBE2D1
Ubiquitin-conjugating enzyme E2 D1.
    
  0.608
KPNA4
Importin subunit alpha-4/3.
    
 
 0.598
ESR1
LOW QUALITY PROTEIN: estrogen receptor.
    
 0.595
BECN1
Beclin-1.
    
 0.552
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
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