Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LPXNLeupaxin isoform X1. (382 aa)    
Predicted Functional Partners:
VCL
Vinculin isoform X1.
   
 0.961
PTK2
Focal adhesion kinase 1 isoform X1.
    
 0.919
CRK
Adapter molecule crk isoform X1.
    
 0.893
PTK2B
Protein tyrosine kinase 2 beta.
    
 0.892
BCAR1
LOW QUALITY PROTEIN: breast cancer anti-estrogen resistance protein 1.
    
 0.871
PARVA
Alpha-parvin isoform X1.
   
 0.866
PARVB
Beta-parvin isoform X1.
   
 0.866
YES1
Tyrosine-protein kinase Yes.
    
 0.840
SRC
Proto-oncogene tyrosine-protein kinase Src isoform X1.
    
 0.840
GIT1
G protein-coupled receptor kinase interactor 1.
    
 
 0.829
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
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