Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KRT16Keratin, type I cytoskeletal 16-like. (455 aa)    
Predicted Functional Partners:
KRT8
Keratin, type II cytoskeletal 8.
   
 0.699
UNC79
Unc-79 homolog, NALCN channel complex subunit.
   
 0.590
PPL
Periplakin.
   
 0.475
KRT7
Keratin, type II cytoskeletal 7.
   
 0.452
LGR5
Leucine rich repeat containing G protein-coupled receptor 5.
    
 0.442
EIF4A3
Eukaryotic initiation factor 4A-III.
    
 0.434
ENSPCIP00000001929
annotation not available
   
 0.417
KRT5
LOW QUALITY PROTEIN: keratin, type II cytoskeletal 5-like.
   
 0.417
KRT6B
Keratin, type II cytoskeletal 6B.
   
 0.417
KRT3
Keratin 3.
   
 0.417
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
Server load: low (14%) [HD]