STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HCN4Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4. (1177 aa)    
Predicted Functional Partners:
SCN2A
Sodium channel protein type 2 subunit alpha isoform X1.
   
 0.905
HCN2
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2.
  
  
 
0.901
TBX18
LOW QUALITY PROTEIN: T-box transcription factor TBX18.
      
 0.636
KCNE3
Potassium voltage-gated channel Isk-related subfamily E member 3.
     
 0.492
KCNJ8
Potassium inwardly-rectifying channel subfamily J member 8.
      
 0.482
SCN5A
Sodium channel protein type 5 subunit alpha-like isoform X1.
   
 
 0.458
TBX5
T-box transcription factor TBX5 isoform X1.
   
  
 0.444
ABCC9
LOW QUALITY PROTEIN: ATP-binding cassette sub-family C member 9.
   
 
 0.443
KCND3
Potassium voltage-gated channel Shal-related subfamily D member 3.
   
 0.443
SCN2B
Voltage-gated sodium channel type II beta.
   
  
 0.433
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.