STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LRP5Low density lipoprotein receptor-related protein 5/6. (1603 aa)    
Predicted Functional Partners:
DKK1
Dickkopf-related protein 1.
    
 0.994
SOST
Sclerostin.
    
 0.989
FZD4
LOW QUALITY PROTEIN: frizzled-4.
    
 0.982
LRP6
Low-density lipoprotein receptor-related protein 6 isoform X1.
  
 
0.982
DKK4
Dickkopf-related protein 4.
    
 0.980
DKK2
Dickkopf-related protein 2 isoform X1.
    
 0.980
FZD5
Frizzled 5/8.
    
 0.956
DVL2
LOW QUALITY PROTEIN: segment polarity protein dishevelled homolog DVL-2.
   
 0.952
DVL3
Segment polarity protein dishevelled homolog DVL-3 isoform X1.
   
 0.952
FZD2
Frizzled 2.
    
 0.950
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.