Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ANGPT2Angiopoietin-2 isoform X1. (495 aa)    
Predicted Functional Partners:
TEK
Endothelial-specific receptor tyrosine kinase.
   
 0.999
ANGPT1
LOW QUALITY PROTEIN: angiopoietin-1.
     
0.947
ANGPT4
Angiopoietin 4.
  
  
0.929
TIE1
Tyrosine-protein kinase receptor Tie-1.
   
 0.892
KDR
LOW QUALITY PROTEIN: vascular endothelial growth factor receptor 2.
   
 0.886
FLT1
LOW QUALITY PROTEIN: vascular endothelial growth factor receptor 1.
   
 0.813
PDGFRB
Platelet-derived growth factor receptor beta isoform X1.
    
 0.802
FLT4
Vascular endothelial growth factor receptor 3.
   
 0.799
KIT
Mast/stem cell growth factor receptor Kit isoform X1.
   
 0.743
PDGFRA
Platelet-derived growth factor receptor alpha.
   
 0.733
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
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