Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
NEDD4LE3 ubiquitin-protein ligase NEDD4-like isoform X1. (1297 aa)    
Predicted Functional Partners:
SCNN1B
Amiloride-sensitive sodium channel subunit beta isoform X1.
    
 0.996
SGK1
Serum/glucocorticoid regulated kinase 1.
   
 0.996
SCNN1G
Amiloride-sensitive sodium channel subunit gamma.
    
 0.994
SCNN1A
Amiloride-sensitive sodium channel subunit alpha isoform X1.
    
 0.990
SMAD7
Mothers against decapentaplegic homolog 7.
    
 0.971
NEDD4
E3 ubiquitin-protein ligase NEDD4 isoform X1.
  
 
0.962
SFN
14-3-3 protein sigma.
    
 0.945
UBE2D1
Ubiquitin-conjugating enzyme E2 D1.
    
 0.932
DLG3
Discs large MAGUK scaffold protein 3.
    
 0.927
SCNN1D
Amiloride-sensitive sodium channel subunit delta.
    
 0.906
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
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