Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
PLK5Inactive serine/threonine-protein kinase PLK5. (582 aa)    
Predicted Functional Partners:
BUB1
Mitotic checkpoint serine/threonine-protein kinase BUB1.
   
 0.915
KIF23
Kinesin-like protein KIF23 isoform X1.
   
 0.912
CDC20B
Cell division cycle protein 20 homolog B.
   
 0.872
CDC20
Cell division cycle protein 20 homolog isoform X1.
   
 0.872
FOXM1
Forkhead box protein M1 isoform X1.
   
 0.859
BORA
LOW QUALITY PROTEIN: protein aurora borealis.
   
 0.852
INCENP
Inner centromere protein isoform X1.
   
 0.845
ESPL1
Separase.
   
 0.843
BUB1B
Mitotic checkpoint serine/threonine-protein kinase BUB1 beta isoform X1.
   
 0.832
ERCC6L
DNA excision repair protein ERCC-6-like.
   
 0.822
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
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