Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SHPRHE3 ubiquitin-protein ligase SHPRH isoform X1. (1696 aa)    
Predicted Functional Partners:
RAD18
E3 ubiquitin-protein ligase RAD18 isoform X1.
    
 0.964
PCNA
Proliferating cell nuclear antigen.
  
 0.960
PGM2
Phosphoglucomutase / phosphopentomutase.
   
   0.757
MYSM1
Histone H2A deubiquitinase MYSM1 isoform X1.
   
 0.692
SLCO1A2
Solute carrier organic anion transporter family member 1A2.
   
    0.692
ENSPCIP00000021063
annotation not available
    
 0.692
UBE2V2
Ubiquitin-conjugating enzyme E2 variant 2.
    
 0.692
ENSPCIP00000036957
annotation not available
    
 0.692
HLTF
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A3.
   
 
 0.671
BIRC6
Baculoviral IAP repeat-containing protein 6 isoform X1.
   
 0.664
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
Server load: low (14%) [HD]