STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PCSK4Proprotein convertase subtilisin/kexin type 4. (858 aa)    
Predicted Functional Partners:
MMP11
Matrix metallopeptidase 11.
    
 0.660
TGFB1
Transforming growth factor beta-1.
   
 0.619
PROC
Vitamin K-dependent protein C isoform X1.
   
 
 0.618
FBN1
Fibrillin 1.
   
 
 0.615
F2
Coagulation factor II (thrombin).
   
 
 0.609
PDGFB
Platelet-derived growth factor subunit B isoform X1.
   
 
 0.574
PROS1
Vitamin K-dependent protein S isoform X1.
     
 0.568
F10
Coagulation factor X.
   
 
 0.565
COL25A1
Collagen alpha-1(XXV) chain isoform X1.
    
 0.555
GAS6
Growth arrest-specific protein 6.
   
 
 0.544
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.