Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
PCSK4Proprotein convertase subtilisin/kexin type 4. (858 aa)    
Predicted Functional Partners:
NOTCH1
LOW QUALITY PROTEIN: neurogenic locus notch homolog protein 1.
   
 0.825
MMP14
LOW QUALITY PROTEIN: matrix metalloproteinase-14.
    
 0.811
MMP11
Matrix metallopeptidase 11.
    
 0.808
F2
Coagulation factor II (thrombin).
   
 
 0.796
MMP15
Matrix metalloproteinase-15 (membrane-inserted).
    
 0.787
PROC
Vitamin K-dependent protein C isoform X1.
   
 
 0.774
PDGFB
Platelet-derived growth factor subunit B isoform X1.
   
 
 0.769
TGFB1
Transforming growth factor beta-1.
   
 0.761
PROS1
Vitamin K-dependent protein S isoform X1.
     
 0.758
FBN1
Fibrillin 1.
   
 0.752
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
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