Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CCNA2Cyclin-A2. (440 aa)    
Predicted Functional Partners:
CDK2
Cyclin-dependent kinase 2 isoform X1.
   
 0.999
CDK1
Cyclin-dependent kinase 1.
   
 0.999
CDC6
LOW QUALITY PROTEIN: cell division control protein 6 homolog.
   
 0.998
CDKN1A
Cyclin-dependent kinase inhibitor 1 isoform X1.
   
 0.997
RB1
Retinoblastoma-associated protein isoform X1.
   
 0.997
E2F1
Transcription factor E2F1.
   
 0.995
CCNA1
LOW QUALITY PROTEIN: cyclin-A1.
  
 
0.993
FZR1
Cell division cycle 20-like protein 1, cofactor of APC complex.
   
 0.992
CENPA
LOW QUALITY PROTEIN: histone H3-like centromeric protein A.
   
 0.989
CDKN1B
Cyclin-dependent kinase inhibitor 1B isoform X1.
   
 0.989
Your Current Organism:
Phascolarctos cinereus
NCBI taxonomy Id: 38626
Other names: P. cinereus, koala
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